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Modulation of the toxicity and antitumour activity of alkylating drugs by steroids.

The steroids prednisolone and progesterone significantly altered the therapeutic indices of the alkylating agents, nitrogen mustard, melphalan, cyclophosphamide, phenyl acetic mustard and chlorambucil. For nitrogen mustard, chlorambucil and phenyl acetic mustard, prednisolone reduced host toxicity i...

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Détails bibliographiques
Auteurs principaux: Shepherd, R., Harrap, K. R.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1982
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2010934/
https://ncbi.nlm.nih.gov/pubmed/7073935
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