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Syngeneic immune response to rat tracheal epithelial cells transformed in vitro by N-methyl-N-nitro-N-nitrosoguanidine.

Two cell lines (2-10-1 and 8-10-2) derived by exposure to primary tracheal explants to MNNG in vitro were not tumorigenic in syngeneic F-344 rats or athymic BALB/c (nu/nu) mice at early passage, but became tumorigenic at late passage. These cell lines are therefore suited to study the expression of...

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Autori principali: Braslawsky, G. R., Steele, V., Kennel, S. J., Nettesheim, P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1981
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2010736/
https://ncbi.nlm.nih.gov/pubmed/7272190
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