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Initiation and promotion at different ages and doses in 2200 mice. II. Decrease in promotion by TPA with ageing.

Using the data described in Paper I, we compare the effects of the same treatment timings and doses given at different ages. Initiation with DMBA at 68 weeks of age, followed 3 weeks later by TPA, has a significantly (P less than 0.0001) less rapid effect on subsequent tumour incidence than does ini...

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Detalhes bibliográficos
Main Authors: Stenbäck, F., Peto, R., Shubik, P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2010654/
https://ncbi.nlm.nih.gov/pubmed/6789854
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