Differential Contribution of Toll-Like Receptors 4 and 2 to the Cytokine Response to Salmonella enterica Serovar Typhimurium and Staphylococcus aureus in Mice

The contribution of murine Toll-like receptors 2 and 4 (TLR2 and -4, respectively) to cytokine induction by heat-killed bacteria was analyzed in vitro and in vivo. Gram-negative bacteria induced cytokines primarily via TLR4; the contribution of TLR2 was only minor. Neither TLR4 nor, surprisingly, TL...

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Bibliographische Detailangaben
Hauptverfasser: Lembo, Annalisa, Kalis, Christoph, Kirschning, Carsten J., Mitolo, Vincenzo, Jirillo, Emilio, Wagner, Hermann, Galanos, Chris, Freudenberg, Marina A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Host Response and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC201051/
https://ncbi.nlm.nih.gov/pubmed/14500530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.10.6058-6062.2003
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