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Tumour-necrosis factor from the rabbit. IV. Purification and chemical characterization.

Serum from rabbits with BCG/endotoxin-induced shock is growth inhibitory or cytotoxic to a range ot tumour cell lines. The active component, tumour-necrosis factor (TNF), has been purified 1000-fold by sequential salt precipitation, ion-exchange chromatography and gel-filtration. TNF had a mol. wt o...

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Detalhes bibliográficos
Main Authors: Matthews, N., Ryley, H. C., Neale, M. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2010414/
https://ncbi.nlm.nih.gov/pubmed/7426345
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