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Oxygen-dependent free radicals in spermine oxidation cytostasis and chemiluminescence and the role of superoxide dismutase

Spermine interacted with serum polyamine oxidase (PAO) to arrest proliferation of cultured Bri8 lymphocytes. Arrest was independent of catalase activity and was not directly due to an H(2)O(2) byproduct. Arrest was averted by 3-hydroxybenzyloxyamine, which inactivates the pyridoxal co-factor of PAO....

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Bibliographic Details
Main Authors: Gaugas, J. M., Dewey, D. L.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1980
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2010368/
https://ncbi.nlm.nih.gov/pubmed/7426319
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