The heat shock protein 90 of Plasmodium falciparum and antimalarial activity of its inhibitor, geldanamycin
BACKGROUND: The naturally occurring benzoquinone ansamycin compound, geldanamycin (GA), is a specific inhibitor of heat shock protein 90 (Hsp90) and is a potential anticancer agent. Since Plasmodium falciparum has been reported to have an Hsp90 ortholog, we tested the possibility that GA might inhib...
Guardado en:
| Publicado en: | Malar J |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BMC
2003
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC201030/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14514358/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1475-2875-2-30 |
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