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Effect of methotrexate concentration and exposure time on mammalian cell survival in vitro.

Chinese hamster, HeLa and HAK cells were treated with methotrexate (MTX) to determine the dependence of its effect on drug concentration and exposure time. With a broad range of survival curves for Chinese hamster cells, cell survival is an exponential function of exposure time and a power function...

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Detalhes bibliográficos
Main Authors: Eichholtz, H., Trott, K. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2010205/
https://ncbi.nlm.nih.gov/pubmed/7370167
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