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The penetration of misonidazole into spontaneous canine tumours.

The hypoxic cell-radiosensitizing drug misonidazole (1-(2-nitroimidazol-1-yl)-3-methoxypropan -2 -ol, Ro 07-0582, MIS) was administered at a dose of 150 mg/kg i.v. to 6 dogs bearing spontaneous tumours, and the resulting tumour concentrations were measured to HPLC analysis. In 4 dogs it was possible...

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Bibliografische gegevens
Hoofdauteurs: White, R. A., Workman, P., Owen, L. N., Bleehen, N. M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 1979
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2010015/
https://ncbi.nlm.nih.gov/pubmed/289406
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