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Modification of the immunogenicity and antigenicity of rat hepatoma cells. I. Cell-surface stabilization with glutaraldehyde.

gamma-Irradiated rat hepatoma cells are immunogenic in syngeneic WAB/Not rats, so that immunized animals are protected against tumour-cell challenge and circulating tumour-specific antibody is produced. Treatment of the immunizing cells with glutaraldehyde at concentrations of 0.001% or greater for...

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Detalles Bibliográficos
Main Authors: Price, M. R., Dennick, R. G., Robins, R. A., Baldwin, R. W.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1979
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2009992/
https://ncbi.nlm.nih.gov/pubmed/109110
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