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Radiosensitization of E. coli B/r by the cytotoxic agent procarbazine: a hypoxic cell sensitizer preferentially toxic to aerobic cells and easily oxidized.

Procarbazine has been shown to be a hypoxic cell sensitizer of moderate ability in E. coli B/r, with an achievable enhancement ratio of 1.4 at subtoxic concentrations. The drug appears to act in a manner similar to the expected with the electron-affinic radiosensitizers. However, procarbazine and th...

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Enregistré dans:
Détails bibliographiques
Auteur principal: Roberts, P. B.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1979
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2009976/
https://ncbi.nlm.nih.gov/pubmed/375966
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