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Phase-specific cytotoxicity in vivo of hydroxyurea on murine fibrosarcoma cells synchronized by centrifugal elutriation.

The S-phase-specific cytotoxicity of hydroxyurea (HU) was tested on synchronized murine fibrosarcoma (FSa) cells lodged in the lungs of C3Hf/Bu mice. FSa cells from primary asynchronous cultures were separated and synchronized on the basis of size by centrifugal elutriation. Flow microfluorometry (F...

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Detalhes bibliográficos
Main Authors: Grdina, D. J., Sigdestad, C. P., Peters, L. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2009858/
https://ncbi.nlm.nih.gov/pubmed/435364
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