Peroxisome proliferator-activated receptor-γ haploinsufficiency enhances B cell proliferative responses and exacerbates experimentally induced arthritis

Peroxisome proliferator–activated receptor-γ (PPARγ) controls adipogenesis and glucose metabolism. It was reported recently that PPARγ activation by its agonistic ligands modifies lymphocyte function. Since synthetic ligands are known to exert their effect via PPARγ-dependent and -independent pathwa...

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Pubblicato in:	J Clin Invest
Autori principali:	Setoguchi, Keigo, Misaki, Yoshikata, Terauchi, Yasuo, Yamauchi, Toshimasa, Kawahata, Kimito, Kadowaki, Takashi, Yamamoto, Kazuhiko
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 2001
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC200985/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11733562/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI13202
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