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Influence of misonidazole on the incidence of radiation-induced intestinal tumours in mice.

C57BL mice were given local irradiation to 2 cm2 of the lower abdomen in the dose range 16--24 Gy. There were some early deaths, but mice dying between 50--240 days predominantly developed invasive adenocarcinomas of the intestine. When the radiosensitizer misonidazole was given in a single dose sho...

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Bibliographic Details
Main Authors: Rostom, A. Y., Kauffman, S. L., Steel, G. G.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1978
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2009771/
https://ncbi.nlm.nih.gov/pubmed/728340
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