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Oncogenic transformation in vitro by the hypoxic cell sensitizer misonidazole.

The hypoxic cell sensitizer Misonidazole (Ro-07-0582) induces oncogenic transformations in the C3H/10T1/2 mouse embryo cell line cultured in vitro. A drug concentration of 0.4 mM applied to aerated cells for 3 or 6 days results in a transformation rate comparable to that observed following an X-ray...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Miller, R. C., Hall, E. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1978
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2009745/
https://ncbi.nlm.nih.gov/pubmed/708572
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