Endocytosis of the antiprotease aprotinin by Landschütz ascites carcinoma cells and its effects in vitro and in vivo.

Aprotinin was bound and endocytosed by Landschütz ascites carcinoma (LAC) cells in vitro. Addition of the antiprotease to cultures of these cells led to a dose-dependent growth-inhibitory and cytotoxic effect. In mice inoculated with LAC cells and treated with aprotinin there was a transient reducti...

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Главные авторы: Thomson, A. W., Tweedie, D. J., Pugh-Humphreys, R. G., Arthur, M.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 1978
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2009670/
https://ncbi.nlm.nih.gov/pubmed/308375
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