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Chemical modifications of the protein of carcinoembryonic antigen: associated changes in immunological activity and conformation.

Chemical substitution of the exposed residues of tryptophan, tyrosine, histidine and arginine in carcinoembryonic antigen (CEA), using appropriately selective reagents, caused no significant change in the capacity of the antigen to bind to anti-CEA serum. However, treatments of CEA with 2-hydroxy-5-...

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Detalhes bibliográficos
Main Authors: Westwood, J. H., Thomas, P., Edwards, R. G., Scopes, P. M., Barrett, M. W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2009592/
https://ncbi.nlm.nih.gov/pubmed/629857
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