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Influence of repeated liver regeneration on hepatic carcinogenesis by diethylnitrosamine in mice.

In mice given a single dose of diethylnitrosamine, a hepatonecrotic dose of carbon tetrachloride, 5 weeks after dosing with DEN and repeated 6 times at 4-weekly intervals, augmented the tumour yield in the livers. A single hepatonecrotic dose of CCl4 24 h before a single dose of DEN also increased t...

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Autors principals: Poound, A. W., McGuire, L. J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1978
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2009550/
https://ncbi.nlm.nih.gov/pubmed/646930
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