Requirement for the L-type Ca(2+) channel α(1D) subunit in postnatal pancreatic β cell generation

Pancreatic β cells are the source of insulin, which directly lowers blood glucose levels in the body. Our analyses of α(1D) gene-knockout (α(1D)(–/–)) mice show that the L-type calcium channel, α(1D), is required for proper β cell generation in the postnatal pancreas. Knockout mice were characterist...

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Hauptverfasser: Namkung, Yoon, Skrypnyk, Nataliya, Jeong, Myung-Jin, Lee, Taehoon, Lee, Myung-Shik, Kim, Hyung-Lae, Chin, Hemin, Suh, Pann-Ghill, Kim, Sung-Sook, Shin, Hee-Sup
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2001
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC200955/
https://ncbi.nlm.nih.gov/pubmed/11581302
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