Accelerated apoptosis in the Timp-3–deficient mammary gland

The proapoptotic proteinase inhibitor TIMP-3 is the only molecule of this family thought to influence cell death. We examined epithelial apoptosis in TIMP-3–deficient mice during mammary gland involution. Lactation was not affected by the absence of TIMP-3, but glandular function, as measured by gla...

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Main Authors: Fata, Jimmie E., Leco, Kevin J., Voura, Evelyn B., Yu, Hoi-Ying E., Waterhouse, Paul, Murphy, Gillian, Moorehead, Roger A., Khokha, Rama
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2001
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC200934/
https://ncbi.nlm.nih.gov/pubmed/11560952
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