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Morphological and Biochemical Effects of 1,2-Dimethylhydrazine and 1-Methylhydrazine in Rats and Mice

Single toxic doses of 1,2-dimethylhydrazine induced mild centrilobular necrosis of the liver in rats and mice. Ultrastructural studies showed hepatic nuclear changes including nucleolar microsegregation and changes in the endoplasmic reticulum and mitochondria. 1-Methylhydrazine caused little morpho...

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Detalhes bibliográficos
Main Authors: Hawks, A., Hicks, R. M., Holsman, J. W., Magee, P. N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2009305/
https://ncbi.nlm.nih.gov/pubmed/4469195
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