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Antigen-pulsed dendritic cells expressing macrophage-derived chemokine elicit Th2 responses and promote specific humoral immunity

Macrophage-derived chemokine (MDC) is a potent chemoattractant for antigen-specific T lymphocytes. We hypothesized that Adenovirus- (Ad-) transduced dendritic cells (DCs) overexpressing MDC would enhance the T cell–mediated humoral immune response specific for antigens presented by the DC. We challe...

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Autori principali: Kikuchi, Toshiaki, Crystal, Ronald G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC200925/
https://ncbi.nlm.nih.gov/pubmed/11560961
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