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The structure of mitogen-activated protein kinase p38 at 2.1-Å resolution

The structure of mitogen-activated protein (MAP) kinase p38 has been solved at 2.1-Å to an R factor of 21.0%, making p38 the second low activity MAP kinase solved to date. Although p38 is topologically similar to the MAP kinase ERK2, the phosphorylation Lip (a regulatory loop near the active site) a...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Wang, Zhulun, Harkins, Paul C., Ulevitch, Richard J., Han, Jiahuai, Cobb, Melanie H., Goldsmith, Elizabeth J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20087/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9122194/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.6.2327
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