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Reversal of Methotrexate Toxicity in Mice by 5-Methyltetrahydrofolic Acid
1. Mice have been compeletly protected against the lethal effects of repeated injections of methotrexate by 5-methyltetrahydrofolic acid. Methotrexate-resistant cells probably owe their resistance to their high content of this substance. 2. Daily small doses were much more effective than fewer but l...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
1970
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2008620/ https://ncbi.nlm.nih.gov/pubmed/5312191 |
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