The La antigen binds 5′ noncoding region of the hepatitis C virus RNA in the context of the initiator AUG codon and stimulates internal ribosome entry site-mediated translation

Translation initiation of the hepatitis C virus (HCV) RNA genome occurs through an internal ribosome entry site in a cap-independent manner. Here, we have examined the interaction between La antigen and the HCV 5′ noncoding region (5′NCR). In this analysis, competitor RNAs derived from HCV 5′NCR car...

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Bibliographic Details
Main Authors: Ali, Naushad, Siddiqui, Aleem
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences of the USA 1997
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC20073/
https://ncbi.nlm.nih.gov/pubmed/9122180
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