Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models

Although immunosuppressant immunophilin ligands promote neurite outgrowth in vitro, their neurotrophic activities are clearly independent of their immunosuppressive activity. In the present report, a novel nonimmunosuppressive immunophilin ligand, GPI-1046 (3-(3-pyridyl)-1-propyl (2S)-1-(3,3-dimethy...

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Detalhes bibliográficos
Main Authors: Steiner, Joseph P., Hamilton, Gregory S., Ross, Douglas T., Valentine, Heather L., Guo, Hongzhi, Connolly, Maureen A., Liang, Shi, Ramsey, Cynthia, Li, Jia-He J., Huang, Wei, Howorth, Pamela, Soni, Rajat, Fuller, Michael, Sauer, Hans, Nowotnik, Alison C., Suzdak, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20035/
https://ncbi.nlm.nih.gov/pubmed/9050897
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