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Human INT6/eIF3e is required for nonsense-mediated mRNA decay

The mammalian integration site 6 (INT6) protein has been implicated in breast carcinogenesis and characterized as the eIF3e non-core subunit of the translation initiation factor eIF3, but its role in this complex is not known. Here, we show that INT6 knockdown by RNA interference strongly inhibits n...

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Bibliografiske detaljer
Main Authors: Morris, Christelle, Wittmann, Jürgen, Jäck, Hans-Martin, Jalinot, Pierre
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2002529/
https://ncbi.nlm.nih.gov/pubmed/17468741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400955
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