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Human INT6/eIF3e is required for nonsense-mediated mRNA decay
The mammalian integration site 6 (INT6) protein has been implicated in breast carcinogenesis and characterized as the eIF3e non-core subunit of the translation initiation factor eIF3, but its role in this complex is not known. Here, we show that INT6 knockdown by RNA interference strongly inhibits n...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2002529/ https://ncbi.nlm.nih.gov/pubmed/17468741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400955 |
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