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A(1) Receptor and Adenosinergic Homeostatic Regulation of Sleep-Wakefulness: Effects of Antisense to the A(1) Receptor in the Cholinergic Basal Forebrain

We hypothesized that adenosine, acting via the A(1) receptor, is a key factor in the homeostatic control of sleep. The increase in extracellular levels of adenosine during prolonged wakefulness is thought to facilitate the transition to sleep by reducing the discharge activity of wakefulness-promoti...

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Autors principals: Thakkar, Mahesh M., Winston, Stuart, McCarley, Robert W.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2002519/
https://ncbi.nlm.nih.gov/pubmed/12764116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-10-04278.2003
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