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Choline deficient diet enhances the initiating and promoting effects of methapyrilene hydrochloride in rat liver as assayed by the induction of gamma-glutamyltranspeptidase-positive hepatocyte foci.

Earlier we demonstrated that short-term feeding of methapyrilene hydrochloride (MPH) and of a choline deficient (CD) diet to rats induced peroxidative damage of microsomal membrane lipids of liver cells. In the present study, we investigated whether a CD diet modifies the extent of MPH-induced lipid...

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Bibliographic Details
Main Authors: Perera, M. I., Katyal, S. L., Shinozuka, H.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1987
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2002423/
https://ncbi.nlm.nih.gov/pubmed/2893639
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