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New histological observations in spontaneously developing osteoarthritis in the STR/ORT mouse questioning its acceptability as a model of human osteoarthritis.

Naturally developing spontaneous osteoarthritis (OA) is seen in a number of small animals one of which is the STR/ORT mouse, an accepted model of human OA. A histological evaluation of the patello-femoral joints of 37 male STR/ORT mice has shown features that are inconsistent with the disease in hum...

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Hlavní autoři: Das-Gupta, E. P., Lyons, T. J., Hoyland, J. A., Lawton, D. M., Freemont, A. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2002252/
https://ncbi.nlm.nih.gov/pubmed/8292560
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