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Alpha-2-macroglobulin as the major defence in acute pseudomonal septic shock in the guinea-pig model.

An intravenous injection of 1.2 mg/kg of Pseudomonas aeruginosa elastase induces immediate lethal shock in guinea-pigs. In the present study, alpha-2-macroglobulin (alpha 2M) was shown to be the major factor in guinea-pig plasma that inhibits the enzymatic activity of elastase in vitro. Depletion of...

詳細記述

保存先:
書誌詳細
主要な著者: Khan, M. M., Shibuya, Y., Nakagaki, T., Kambara, T., Yamamoto, T.
フォーマット: Artigo
言語:Inglês
出版事項: 1994
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2002234/
https://ncbi.nlm.nih.gov/pubmed/7524612
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