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Chemosensitization by misonidazole in CCNU-treated spheroids and tumours.

Misonidazole has been demonstrated to enhance the cytotoxicity of several common antineoplastic drugs in vitro and in vivo, and its mechanism of action as a chemosensitizer, though still unknown, is thought to be dependent upon hypoxia. We have used fluorescence-activated cell sorting to evaluate ch...

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Hlavní autoři: Durand, R. E., Chaplin, D. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1987
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2002149/
https://ncbi.nlm.nih.gov/pubmed/3663461
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