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Does allopurinol prevent myocardial injury as a result of hypoxia-re-oxygenation in rats?

We made use of the xanthine oxidase inhibitor allopurinol and examined changes related to myocardial injury of the rat heart during hypoxia-re-oxygenation. The rat heart was perfused using the Langendorff method. With low-oxygen perfusion for 60 min in a solution saturated with mixed gases of 95% N2...

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Detalhes bibliográficos
Main Authors: Miwa-Nishimura, N., Kanaide, H., Abe, S., Nakamura, M.
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001971/
https://ncbi.nlm.nih.gov/pubmed/2206993
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