LPS antagonism reduces graft-versus-host disease and preserves graft-versus-leukemia activity after experimental bone marrow transplantation

Acute graft-versus-host disease (GVHD) and leukemic relapse remain the two major obstacles to successful outcomes after allogeneic bone marrow transplantation (BMT). Recent studies have demonstrated that the loss of gastrointestinal tract integrity, and specifically the translocation of LPS into the...

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Autors principals: Cooke, Kenneth R., Gerbitz, Armin, Crawford, James M., Teshima, Takanori, Hill, Geoffrey R., Tesolin, Amy, Rossignol, Daniel P., Ferrara, James L.M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2001
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC200193/
https://ncbi.nlm.nih.gov/pubmed/11413166
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