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Internalization of a monoclonal antibody against human breast cancer by immunoelectron microscopy.

Using an avidin-gold conjugate, the binding and internalization of the biotinylated anti-breast cancer monoclonal antibody MBr1 in MCF-7 cells were examined. After labelling MCF-7 cells at 0 degrees C, MBr1 was found to specifically bind to the entire cell surface. MBr1 distribution was diffused in...

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Detalhes bibliográficos
Main Authors: Della Torre, G., Canevari, S., Orlandi, R., Colnaghi, M. I.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001702/
https://ncbi.nlm.nih.gov/pubmed/3580261
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