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Characterization of a doxorubicin-resistant murine melanoma line: studies on cross-resistance and its circumvention.

A B16 mouse melanoma cell line resistant to doxorubicin was obtained by continuous in vitro exposure to the drug. The ID50 for this line was 200 times higher than that for the parental cell line. The resistant cell line had some biological characteristics similar to those of the sensitive parental c...

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Bibliographic Details
Main Authors: Supino, R., Prosperi, E., Formelli, F., Mariani, M., Parmiani, G.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1986
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001650/
https://ncbi.nlm.nih.gov/pubmed/3730255
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