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Influence of perinatal nicotine administration on transplacental carcinogenesis in Sprague Dawley rats by N-methylnitrosourea.

The administration of nicotine during the perinatal stages of life resulted in a significant decrease in tumours occurring after transplacental induction by N-methylnitrosourea (MNU). The overall tumour incidence following p.o. application of MNU to dams was 85% in rats of the F1-generation, the mai...

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Bibliografiske detaljer
Main Authors: Berger, M. R., Petru, E., Habs, M., Schmähl, D.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1987
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001561/
https://ncbi.nlm.nih.gov/pubmed/3814474
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