Interaction of bleomycin, hyperthermia and a calmodulin inhibitor (trifluoperazine) in mouse tumour cells: II. DNA damage, repair and chromatin changes.

We have reported in the preceding paper that the treatment of plateau phase mouse EMT6 tumour cells with a combination of hyperthermia (HT; 44 degrees C) and trifluoperazine (TFP; 30 micrograms ml-1; an inhibitor of calmodulin) greatly enhances the cytotoxicity of the antitumour drug belomycin (BLM)...

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Detalhes bibliográficos
Main Authors: Smith, P. J., Mircheva, J., Bleehen, N. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1986
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001464/
https://ncbi.nlm.nih.gov/pubmed/2418859
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