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Morphological and isoenzymatic differentiation of B-chronic lymphocytic leukaemia cells induced by phorbolester.

Fresh leukaemia cells from the peripheral blood of 6 patients with B-chronic lymphocytic leukaemia (CLL) were cultured in the continuous presence of the phorbolester 12-O-tetradecanoylphorbol 13-acetate (TPA) for in vitro induction of differentiation. Upon treatment with TPA the cells showed distinc...

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Detalhes bibliográficos
Main Authors: Drexler, H. G., Klein, M., Bhoopalam, N., Gaedicke, G., Minowada, J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001325/
https://ncbi.nlm.nih.gov/pubmed/3485441
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