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ENDOCANNABINOID-MEDIATED LONG-TERM PLASTICITY REQUIRES cAMP/PKA SIGNALING AND RIM1α

Endocannabinoids (eCB) have emerged as key activity-dependent signals that, by activating presynaptic cannabinoid receptors (CB1) coupled to G(i/o) protein, can mediate short-term and long-term synaptic depression (LTD). While the presynaptic mechanisms underlying eCB-dependent short-term depression...

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Detalhes bibliográficos
Main Authors: Chevaleyre, Vivien, Heifets, Boris D., Kaeser, Pascal S., Südhof, Thomas C., Castillo, Pablo E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001295/
https://ncbi.nlm.nih.gov/pubmed/17553427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2007.05.020
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