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Chromatography of Proteins on Charge-Variant Ion Exchangers and Implications for Optimizing Protein Uptake Rates

Intraparticle transport of proteins usually represents the principal resistance controlling their uptake in preparative separations. In ion-exchange chromatography two limiting models are commonly used to describe such uptake: pore diffusion, in which only free protein in the pore lumen contributes...

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Bibliografische gegevens
Hoofdauteurs: Langford, John F., Yao, Xuankuo Xu Yan, Maloney, Sean F., Lenhoff, Abraham M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001243/
https://ncbi.nlm.nih.gov/pubmed/17640661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2007.06.028
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