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Global transcriptional responses to cisplatin in Dictyostelium discoideum identify potential drug targets

Dictyostelium discoideum is a useful model for studying mechanisms of cisplatin drug sensitivity. Our previous findings, that mutations in sphingolipid metabolism genes confer cisplatin resistance in D. discoideum and in human cells, raised interest in the resistance mechanisms and their implication...

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Detalhes bibliográficos
Main Authors: Van Driessche, Nancy, Alexander, Hannah, Min, Junxia, Kuspa, Adam, Alexander, Stephen, Shaulsky, Gad
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000517/
https://ncbi.nlm.nih.gov/pubmed/17878305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705996104
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