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Principal component analysis of the pH-dependent conformational transitions of bovine β-lactoglobulin monitored by heteronuclear NMR

To clarify the pH-dependent conformational transitions of proteins, we propose an approach in which structural changes monitored by heteronuclear sequential quantum correlation (HSQC) spectroscopy were analyzed by using a principal component analysis (PCA). We use bovine β-lactoglobulin, a protein w...

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Autors principals: Sakurai, Kazumasa, Goto, Yuji
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000507/
https://ncbi.nlm.nih.gov/pubmed/17878316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702112104
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