Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis

Deregulation of the Myc pathway and deregulation of the Rb pathway are two of the most common abnormalities in human malignancies. Recent in vitro experiments suggest a complex cross-regulatory relationship between Myc and Rb that is mediated through the control of E2F. To evaluate the functional co...

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Hlavní autoři: Opavsky, Rene, Tsai, Shih-Yin, Guimond, Martin, Arora, Anjulie, Opavska, Jana, Becknell, Brian, Kaufmann, Michael, Walton, Nathaniel A., Stephens, Julie A., Fernandez, Soledad A., Muthusamy, Natarajan, Felsher, Dean W., Porcu, Pierluigi, Caligiuri, Michael A., Leone, Gustavo
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000495/
https://ncbi.nlm.nih.gov/pubmed/17881568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706307104
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