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rRNA gene silencing and nucleolar dominance: insights into a chromosome-scale epigenetic on/off switch

Ribosomal RNA (rRNA) gene transcription accounts for most of the RNA in prokaryotic and eukaryotic cells. In eukaryotes, there are hundreds (to thousands) of rRNA genes tandemly repeated head-to-tail within nucleolus organizer regions (NORs) that span millions of basepairs. These nucleolar rRNA gene...

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Detalhes bibliográficos
Main Authors: Preuss, Sasha, Pikaard, Craig S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000449/
https://ncbi.nlm.nih.gov/pubmed/17439825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbaexp.2007.02.005
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