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rRNA gene silencing and nucleolar dominance: insights into a chromosome-scale epigenetic on/off switch
Ribosomal RNA (rRNA) gene transcription accounts for most of the RNA in prokaryotic and eukaryotic cells. In eukaryotes, there are hundreds (to thousands) of rRNA genes tandemly repeated head-to-tail within nucleolus organizer regions (NORs) that span millions of basepairs. These nucleolar rRNA gene...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2000449/ https://ncbi.nlm.nih.gov/pubmed/17439825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbaexp.2007.02.005 |
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