Plasmodium falciparum ookinetes require mosquito midgut chondroitin sulfate proteoglycans for cell invasion

Malaria transmission entails development of the Plasmodium parasite in its insect vector, the Anopheles mosquito. Parasite invasion of the mosquito midgut is the critical first step and involves adhesion to host epithelial cell ligands. Partial evidence suggests that midgut oligosaccharides are impo...

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Main Authors: Dinglasan, Rhoel R., Alaganan, Aditi, Ghosh, Anil K., Saito, Akio, van Kuppevelt, Toin H., Jacobs-Lorena, Marcelo
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000438/
https://ncbi.nlm.nih.gov/pubmed/17873063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706340104
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