Polylactosamine on glycoproteins influences basal levels of lymphocyte and macrophage activation

β1,3-N-acetylglucosaminyltransferase 2 (β3GnT2) is a polylactosamine synthase that synthesizes a backbone structure of carbohydrate structures onto glycoproteins. Here we generated β3GnT2-deficient (β3GnT2(−/−)) mice and showed that polylactosamine on N-glycans was markedly reduced in their immunolo...

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Main Authors: Togayachi, Akira, Kozono, Yuko, Ishida, Hiroyasu, Abe, Sumie, Suzuki, Nami, Tsunoda, Yuki, Hagiwara, Kozue, Kuno, Atsushi, Ohkura, Takashi, Sato, Nobuo, Sato, Takashi, Hirabayashi, Jun, Ikehara, Yuzuru, Tachibana, Kouichi, Narimatsu, Hisashi
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000437/
https://ncbi.nlm.nih.gov/pubmed/17890318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707426104
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