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Toward high-resolution prediction and design of transmembrane helical protein structures

The prediction and design at the atomic level of membrane protein structures and interactions is a critical but unsolved challenge. To address this problem, we have developed an all-atom physical model that describes intraprotein and protein–solvent interactions in the membrane environment. We evalu...

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Autors principals: Barth, P., Schonbrun, J., Baker, D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000396/
https://ncbi.nlm.nih.gov/pubmed/17905872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702515104
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