An In Vitro Model for Lewy Body-Like Hyaline Inclusion/Astrocytic Hyaline Inclusion: Induction by ER Stress with an ALS-Linked SOD1 Mutation

Neuronal Lewy body-like hyaline inclusions (LBHI) and astrocytic hyaline inclusions (Ast-HI) containing mutant Cu/Zn superoxide dismutase 1 (SOD1) are morphological hallmarks of familial amyotrophic lateral sclerosis (FALS) associated with mutant SOD1. However, the mechanisms by which mutant SOD1 co...

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Autors principals: Yamagishi, Satoru, Koyama, Yoshihisa, Katayama, Taiichi, Taniguchi, Manabu, Hitomi, Junichi, Kato, Masaaki, Aoki, Masashi, Itoyama, Yasuto, Kato, Shinsuke, Tohyama, Masaya
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2007
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000355/
https://ncbi.nlm.nih.gov/pubmed/17925878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001030
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