Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex

PTF1a is an unusual basic helix–loop–helix (bHLH) transcription factor that is required for the development of the pancreas. We show that early in pancreatic development, active PTF1a requires interaction with RBPJ, the vertebrate Suppressor of Hairless, within a stable trimeric DNA-binding complex...

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Main Authors: Masui, Toshihiko, Long, Qiaoming, Beres, Thomas M., Magnuson, Mark A., MacDonald, Raymond J.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2007
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Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000326/
https://ncbi.nlm.nih.gov/pubmed/17938243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1575207
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